Highly singlet oxygen generative water-soluble coumarin substituted zinc(II) phthalocyanine photosensitizers for photodynamic therapy

Basit Öğe Kaydı
dc.contributor.authorCamur, Meryem
dc.contributor.authorDurmuş, Mahmut
dc.contributor.authorBulut, Mustafa
dc.date.accessioned2025-10-29T11:23:42Z
dc.date.issued2012
dc.departmentFakülteler, Temel Bilimler Fakültesi, Kimya Bölümü
dc.description.abstractNew tetra-non-peripherally and peripherally ethyl butyrate or butanoic acid and their sodium salts bearing coumarin substituted zinc(II) phthalocyanine complexes have been synthesized and characterized for the first time. Butanoic acid bearing coumarin substituted zinc(II) phthalocyanine complexes and their sodium salts show excellent solubility in aqueous solution. Photophysical and photochemical properties of these phthalocyanines were investigated. General trends are described for photodegradation, fluorescence and singlet oxygen quantum yields as well as fluorescence lifetimes of these compounds. The value of singlet oxygen quantum yields ranged from 0.65 to 0.93 in phosphate-buffered saline + Triton X-100 solution indicating that they can produce singlet oxygen in high efficiency. This study also presented the synthesized water soluble zinc(II) phthalocyanines strongly bind to bovine serum albumin. (c) 2012 Elsevier Ltd. All rights reserved.
dc.description.sponsorshipResearch Foundation of Marmara University, Commission of Scientific Research Project (BAPKO) [FEN-C-YLP-210311-0061]
dc.description.sponsorshipWe are thankful to the Research Foundation of Marmara University, Commission of Scientific Research Project (BAPKO) [FEN-C-YLP-210311-0061] for supporting this study.
dc.identifier.doi10.1016/j.poly.2012.04.034
dc.identifier.endpage103
dc.identifier.issn0277-5387
dc.identifier.issue1
dc.identifier.orcid0000-0002-8720-8087
dc.identifier.scopus2-s2.0-84862115054
dc.identifier.scopusqualityQ2
dc.identifier.startpage92
dc.identifier.urihttps://doi.org/10.1016/j.poly.2012.04.034
dc.identifier.urihttps://hdl.handle.net/20.500.14854/9577
dc.identifier.volume41
dc.identifier.wosWOS:000309096800013
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofPolyhedron
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectPhthalocyanine
dc.subjectCoumarin (2H-1-benzopyran-2-one)
dc.subjectZinc
dc.subjectWater soluble
dc.subjectPhotodynamic therapy
dc.subjectSinglet oxygen
dc.titleHighly singlet oxygen generative water-soluble coumarin substituted zinc(II) phthalocyanine photosensitizers for photodynamic therapy
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Temel Bilimler Fakültesi Koleksiyonu