Click Chemistry for Nanoparticle-Modification

Abstract

Nanotechnology is a new class of material science that has been given great attention by scientists. Nanoparticle materials are formed by the combination of chemistry, materials, and nanotechnology sciences. Nanomaterials find different applications area in almost all science and industrial areas such as food, machines, electronics, chemistry, drugs, etc. One of the most important reasons for the use of nanomaterials in many areas is the ease of chemical modification of the surface of these materials. In chemistry, it is possible to produce a new molecule and modifications by making different combinations with many molecules in the presence of suitable catalysts. “Click” chemistry is one of the significant chemical reactions for the chemical modification of nanomaterials. It is a special reaction in which a series of chemical reactions occur together producing a highly efficient product and minimal by-products. “Click” chemistry, awarded the Nobel Prize in Chemistry in 2022, is widely used in bioconjugation, surface modification, and materials science. In this chapter, information about “click” chemistry methods used in the modification of nanoparticles will be discussed. © 2024 Elsevier B.V., All rights reserved.