Cerium doped magnetite nanoparticles for highly sensitive detection of metronidazole via chemiluminescence assay

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dc.contributor.authorOrooji, Yasin
dc.contributor.authorIrani-nezhad, Mahsa Haddad
dc.contributor.authorHassandoost, Ramin
dc.contributor.authorKhataee, Alireza
dc.contributor.authorPouran, Shima Rahim
dc.contributor.authorJoo, Sang Woo
dc.date.accessioned2025-10-29T11:23:19Z
dc.date.issued2020
dc.departmentFakülteler, Mühendislik Fakültesi, Çevre Mühendisliği Bölümü
dc.description.abstractCerium doped magnetite nanoparticle (CDM) was synthesized via a co-precipitation method and used as the co-reactant of luminol-K3Fe(CN)(6) chemiluminescent system. The physical-chemical features of CDM were studied by XPS, XRD, HRTEM, FESEM, VSM, BET, and FTIR analyses. This simple and highly sensitive nanoprobe enabled the determination of minor concentrations of metronidazole (MNZ). Owing to the quenching efficacy of MNZ in the studied chemiluminescence system, a linear range of 3.47 x 10(-6)-9.37 x 10(-5) mol/L was obtained with a limit of detection of 3.91 x 10(-7) mol/L. This biosensor was used for MNZ detection in human serum samples, which was highly efficient. The outcomes of this study give credit to the proposed biosensor to be applied for detection of MNZ in biological samples. (C) 2020 Elsevier B.V. All rights reserved.
dc.description.sponsorshipUniversity of Tabriz - Nanjing Forestry University [163020139, 163040109, 163020236, NRF-2019R1A5A8080290]
dc.description.sponsorshipNational Research Foundation of Korea
dc.description.sponsorshipThe authors are thankful to the University of Tabriz for the support provided. This work is funded by Nanjing Forestry University [Grant nos. 163020139, 163040109 and 163020236] and the grant no. NRF-2019R1A5A8080290 of the National Research Foundation of Korea.
dc.identifier.doi10.1016/j.saa.2020.118272
dc.identifier.issn1386-1425
dc.identifier.issn1873-3557
dc.identifier.orcid0000-0002-4457-0852
dc.identifier.orcid0000-0002-4673-0223
dc.identifier.orcid0000-0001-6940-5047
dc.identifier.orcid0000-0001-9825-4276
dc.identifier.pmid32229321
dc.identifier.scopus2-s2.0-85082605226
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.saa.2020.118272
dc.identifier.urihttps://hdl.handle.net/20.500.14854/9396
dc.identifier.volume234
dc.identifier.wosWOS:000535905100018
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofSpectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectAntibiotics detection
dc.subjectChemiluminescence
dc.subjectHuman plasma
dc.subjectMagnetic sensor
dc.subjectMetronidazole
dc.titleCerium doped magnetite nanoparticles for highly sensitive detection of metronidazole via chemiluminescence assay
dc.typeArticle

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