The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer

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dc.contributor.authorLo, Pui-Chi
dc.contributor.authorSalome Rodriguez-Morgade, M.
dc.contributor.authorPandey, Ravindra K.
dc.contributor.authorNg, Dennis K. P.
dc.contributor.authorTorres, Tomas
dc.contributor.authorDumoulin, Fabienne
dc.date.accessioned2025-10-29T11:19:57Z
dc.date.issued2020
dc.departmentFakülteler, Temel Bilimler Fakültesi, Kimya Bölümü
dc.description.abstractPhthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
dc.description.sponsorshipResearch Grants Council of the Hong Kong Special Administrative Region [11303517]
dc.description.sponsorshipNIH [PO1CA055791]
dc.description.sponsorshipTPCI Support Grant [P30CA16056]
dc.description.sponsorshipMINECO [CTQ2017-85393-P]
dc.description.sponsorshipERA-NET/MINECO [EuroNanoMed2017-191/PCIN-2017-042]
dc.description.sponsorshipTurkish Academy of Sciences
dc.description.sponsorshipPCL thanks the Research Grants Council of the Hong Kong Special Administrative Region (Project No. 11303517) for support. RKP is thankful to NIH (PO1CA055791) and TPCI Support Grant P30CA16056. MSRM and TT have been supported by MINECO (CTQ2017-85393-P) and ERA-NET/MINECO EuroNanoMed2017-191/PCIN-2017-042. FD is grateful for the support from the Turkish Academy of Sciences.
dc.identifier.doi10.1039/c9cs00129h
dc.identifier.endpage1056
dc.identifier.issn0306-0012
dc.identifier.issn1460-4744
dc.identifier.issue4
dc.identifier.orcid0000-0002-0315-8538
dc.identifier.orcid0000-0001-9335-6935
dc.identifier.orcid0000-0002-9889-4860
dc.identifier.orcid0000-0002-0388-8338
dc.identifier.orcid0000-0002-0002-7049
dc.identifier.orcid0000-0001-9087-960X
dc.identifier.pmid31845688
dc.identifier.scopus2-s2.0-85079736454
dc.identifier.scopusqualityQ1
dc.identifier.startpage1041
dc.identifier.urihttps://doi.org/10.1039/c9cs00129h
dc.identifier.urihttps://hdl.handle.net/20.500.14854/8385
dc.identifier.volume49
dc.identifier.wosWOS:000515511500007
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRoyal Soc Chemistry
dc.relation.ispartofChemical Society Reviews
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20251020
dc.subjectContaining Ruthenium Phthalocyanines
dc.subjectIn-Vitro
dc.subjectZinc Phthalocyanine
dc.subjectConjugate
dc.subjectNanoparticles
dc.subjectDesign
dc.subjectPhotoproperties
dc.subjectDelivery
dc.titleThe unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer
dc.typeReview Article

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