Hydrophilic monomer and crosslinker effects on optical and chemical properties of hydrophobic intraocular lenses (IOLs)

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dc.contributor.authorAki, Deniz
dc.contributor.authorSenel, Esat Can
dc.contributor.authorRad, Monireh Esmaeili
dc.contributor.authorGokmenoglu, Melih Can
dc.contributor.authorOnceyiz, Mesut Celil
dc.contributor.authorNarayan, Roger
dc.contributor.authorGunduz, Oguzhan
dc.date.accessioned2025-10-29T11:12:07Z
dc.date.issued2025
dc.departmentGebze Teknik Üniversitesi
dc.description.abstractAn experimental study was conducted to reduce glistening and minimize posterior capsule opacification (PCO) in hydrophobic intraocular lenses (IOLs). This approach involved the copolymerization of hydrophilic 2-hydroxyethyl acrylate (HEA) at various concentrations with hydrophobic monomers, along with incorporating different amounts of ethylene glycol di-methacrylate (EGDMA) as a crosslinker to optimize the chemical, thermal, and optical properties. Sixteen IOL formulations were synthesized and systematically analyzed using equilibrium water content (EWC) measurements, glass-transition temperature (Tg) measurements, and optical evaluation. Optimizing the balance of hydrophilic monomer and crosslinker effectively eliminates glistening and mitigates PCO while maintaining the essential optical property of hydrophobic IOLs.
dc.description.sponsorshipYuksekogretim Kurulu, 100/2000 program
dc.description.sponsorshipScientific and Technological Research Council of Turkey [118C146]
dc.description.sponsorshipThis work was funded by Yuksekogretim Kurulu, 100/2000 program, Deniz Aki, The Scientific and Technological Research Council of Turkey, 118C146, Monireh Esmaeili Rad
dc.identifier.doi10.1557/s43579-025-00773-2
dc.identifier.endpage849
dc.identifier.issn2159-6859
dc.identifier.issn2159-6867
dc.identifier.issue4
dc.identifier.scopus2-s2.0-105009897321
dc.identifier.scopusqualityQ3
dc.identifier.startpage840
dc.identifier.urihttps://doi.org/10.1557/s43579-025-00773-2
dc.identifier.urihttps://hdl.handle.net/20.500.14854/6130
dc.identifier.volume15
dc.identifier.wosWOS:001523884000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofMrs Communications
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20251020
dc.subjectBiomaterial
dc.subjectPolymer
dc.subjectPolymerization
dc.titleHydrophilic monomer and crosslinker effects on optical and chemical properties of hydrophobic intraocular lenses (IOLs)
dc.typeArticle

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