Towards near-infrared photosensitisation: a photosensitising hydrophilic non-peripherally octasulfanyl-substituted Zn phthalocyanine

Abstract

A Zn(II) phthalocyanine substituted with eight hydroxylated sulfanyl moieties in non-peripheral positions was designed to exhibit properties desired for photodynamic therapy: hydrophilicity, isomeric purity and near-infrared absorption in addition to high singlet oxygen generation. Photophysical and photochemical studies proved to be promising. (c) 2012 Elsevier Ltd. All rights reserved.