Systems Biology Modeling to Study Pathogen-Host Interactions

dc.contributor.authorCesur, Muberra Fatma
dc.contributor.authorDurmus, Saliha
dc.coverage.doi10.1007/978-1-4939-7604-1
dc.date.accessioned2025-10-29T11:33:35Z
dc.date.issued2018
dc.departmentGebze Teknik Üniversitesi
dc.description.abstractPathogen-host interactions (PHIs) underlie the process of infection. The systems biology view of the whole PHI system is superior to the investigation of the pathogen or host separately in understanding the infection mechanisms. Especially, the identification of host-oriented drug targets for the next-generation anti-infection therapeutics requires the properties of the host factors targeted by pathogens. Here, we provide an outline of computational analysis of PHI networks, focusing on the properties of the pathogen-targeted host proteins. We also provide information about the available PHI data and the related Web-based resources.
dc.identifier.doi10.1007/978-1-4939-7604-1_10
dc.identifier.endpage112
dc.identifier.isbn978-1-4939-7604-1
dc.identifier.isbn978-1-4939-7603-4
dc.identifier.issn1064-3745
dc.identifier.issn1940-6029
dc.identifier.orcid0000-0003-2993-0634
dc.identifier.pmid29288450
dc.identifier.scopus2-s2.0-85039906373
dc.identifier.scopusqualityQ4
dc.identifier.startpage97
dc.identifier.urihttps://doi.org/10.1007/978-1-4939-7604-1_10
dc.identifier.urihttps://hdl.handle.net/20.500.14854/12485
dc.identifier.volume1734
dc.identifier.wosWOS:000432981800012
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHumana Press Inc
dc.relation.ispartofHost-Pathogen Interactions: Methods and Protocols
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectPathogen-host interaction
dc.subjectNetwork analysis
dc.subjectComparative interactomics
dc.subjectInfection mechanism
dc.subjectDrug target
dc.titleSystems Biology Modeling to Study Pathogen-Host Interactions
dc.typeBook Chapter

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