A synthetic strategy of P-stereogenic ligands for catalysis: Examples based on cyclotriphosphazenes

Abstract

The discovery of new types of catalyst structures and the development of new efficient synthetic meth-ods for their preparation are an intensively studied research area. Therefore, in this study, chiral cyclot-riphosphazene ligands having P-stereogenic center were synthesized to be effective for catalysis. After the characterization, ligands were used to complex with ruthenium. The catalytic reaction yields of the re-ported complexes in the hydrogenation of acetophenones were investigated. In this study, we developed a reliable synthetic route for the preparation of inorganic-organic chiral catalyst based on cyclophosp-hazene. The preliminary results showed that the chiral ligands produced from rigid cyclotriphosphazene platform might be good candidates for the asymmetric catalyst because of their inherently convenient structure which is regionally and stereochemically controllable for specific functionalization. In this study, we aimed to find clues on the structure-catalyst activity to shed light on future studies. (c) 2022 Elsevier B.V. All rights reserved.