Selective Turn-On Aluminium Ions Detection of NBD(+) Appended Schiff-Base Fluorophore

Abstract

The Al3+ sensor, 7-nitrobenz-2-oxa-1, 3-diazole (NBD) derived fluorescent probe 2-((E)-(4-(phenylamino)benzo[c][1,2,5]oxadiazol-7-ylimino)methyl) phenol (3) was synthesized and characterized by various spectral methods and crystallography. The compound (3) exhibits dual channel (fluorometric and colorimetric) sensor behaviour. It has high selectivity for Al3+ detection, produced significant fluorescence enhancement in the presence of Al3+ ion. It shows ‘‘turn off–on’’ fluorescent responses toward Al3+ in semi aqueous medium. Here, the correlative the properties of a photo sensor (NBD based schiff‘s base 3 with normal NBD derivatives 1, 2) towards Al3+ was studied. The solvent effect and cation sensing properties were investigated from ultraviolet spectroscopy and fluorescence spectroscopic methods. The facile synthetic probe 3 will alternative and open new opportunities in bio-imaging of Al3+ in various cell lines. This will certainly be helpful in understanding the fundamental mechanism of aluminium-induced human diseases. © 2020 Elsevier B.V., All rights reserved.