Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging

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dc.contributor.authorMauriello-Jimenez, Chiara
dc.contributor.authorHenry, Maxime
dc.contributor.authorAggad, Dina
dc.contributor.authorRaehm, Laurence
dc.contributor.authorCattoen, Xavier
dc.contributor.authorMan, Michel Wong Chi
dc.contributor.authorCharnay, Clarence
dc.date.accessioned2025-10-29T11:20:00Z
dc.date.issued2017
dc.departmentFakülteler, Temel Bilimler Fakültesi, Kimya Bölümü
dc.description.abstractPorphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles (BSPOR and BSPHT) were prepared. Their endocytosis in MCF-7 cancer cells was shown with two-photon excited fluorescence (TPEF) imaging. With two-photon excited photodynamic therapy (TPE-PDT), BSPOR was more phototoxic than BSPHT, which in contrast displayed a very high signal for photoacoustic imaging in mice.
dc.description.sponsorshipFrench Embassy in Turkey [Bosphorus 115Z864/35666WL]
dc.description.sponsorshipThe Scientific and Technological Research Council of Turkey (TUBITAK) and the French Embassy in Turkey are gratefully acknowledged for the bilateral Parteneriat Hubert Curien between Turkey and France (project Bosphorus 115Z864/35666WL). ANR nanoptPDT is gratefully acknowledged. Genevieve Conejero and Marc Lartaud are acknowledged for their help with the two-photon bleaching experiment. MGB thanks the region languedoc roussillon for Chercheur d'Avenir grant (2013).
dc.identifier.doi10.1039/c7nr04677d
dc.identifier.endpage16626
dc.identifier.issn2040-3364
dc.identifier.issn2040-3372
dc.identifier.issue43
dc.identifier.orcid0000-0002-8796-3701
dc.identifier.orcid0000-0001-6300-1279
dc.identifier.orcid0000-0001-6733-3801
dc.identifier.orcid0000-0002-5366-8448
dc.identifier.orcid0000-0002-4212-4197
dc.identifier.orcid0000-0002-2529-2105
dc.identifier.orcid0000-0002-0388-8338
dc.identifier.pmid29082396
dc.identifier.scopus2-s2.0-85033794557
dc.identifier.scopusqualityQ1
dc.identifier.startpage16622
dc.identifier.urihttps://doi.org/10.1039/c7nr04677d
dc.identifier.urihttps://hdl.handle.net/20.500.14854/8411
dc.identifier.volume9
dc.identifier.wosWOS:000414960900011
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRoyal Soc Chemistry
dc.relation.ispartofNanoscale
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectSilica Nanoparticles
dc.subjectGold Nanorod
dc.subjectFluorescence
dc.subjectNanomaterials
dc.subjectAbsorption
dc.subjectAgents
dc.titlePorphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging
dc.typeArticle

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