The first example of macrocyclic derivatives of cyclotetraphosphazene

Abstract

The alcoholysis reaction of octachlorocyclotetraphosphazene, N4P4Cl8 (1) with the disodium salt of tetraethyleneglycol gave the first macrocyclic cyclotetraphosphazene derivatives which are bis-ansa structures (2a and 2b). The isolated compound (2a) has been fully characterized by elemental analysis, MALDI-TOF mass spectrometry as well as H-1 and P-31 NMR spectroscopy. The molecular and crystal structure of 2a was determined by single crystal X-Ray diffraction. X-Ray crystallography confirms that the structure of 2a is the cis-bis-ansa isomer. This is the first example of a molecule of a tetrameric cyclophosphazene with a flexible macrocyclic organic substituent suitable for metal complexation.