Three Dimensional (3D) Fabrication of Multilayered Heart Valve Tissues by Stereolithography technique

Abstract

Cardiovascular diseases represent the leading causes of worldwide morbidity and mortality. These diseses causes death of more than 20 million people annually. More than 600,000 cardiovascular surgical interventions are performed every year and this costs around 200 billion dollars. The most prevalent cardiovascular diseases are heart tissue diseases which cause heart attack. One of the most prominent solution for this problem is to develop heart valves and heart tissues that are fabricated by 3D organ biofabrication methodologies such as bioprinters. The purpose of this research is; to fabricate heart valves and endothelial myocard tissues that have high durability and high biocompatibility by the help of stereolithography which is the most trending technique among other 3D bioprinting techniques.