Synthesis of Novel Pyrrolo[3,2-c]carbazole and Dipyrrolo[3,2-c: 2?,3?-g]carbazole Derivatives

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dc.contributor.authorSengul, Ibrahim Fazil
dc.contributor.authorAstarci, Erhan
dc.contributor.authorKandemir, Hakan
dc.date.accessioned2025-10-29T11:19:34Z
dc.date.issued2016
dc.departmentFakülteler, Temel Bilimler Fakültesi, Kimya Bölümü
dc.description.abstractPyrrolocarbazole and dipyrrolocarbazoles have been synthesized via the Hemetsberger indole synthesis, starting from 9-ethyl carbazole-3-carbaldehyde and 9-ethylcarbazole-3,6-dicarbaldeyde, respectively. The pyrrolocarbazole structures were confirmed through H-1 NMR, C-13 NMR, IR, mass spectrometry and single crystal X-ray diffraction techniques. The targeted compounds showed potent in vitro cytotoxicity against human colon cancer HT29 cells.
dc.description.sponsorshipTUBITAK [113Z159]
dc.description.sponsorshipThis work was funded by TUBITAK grant 113Z159 to E.A., I.F.S., and H.K. We thank the NMR facility of Gebze Technical University.
dc.identifier.doi10.1055/s-0035-1560601
dc.identifier.endpage1281
dc.identifier.issn0936-5214
dc.identifier.issn1437-2096
dc.identifier.issue8
dc.identifier.scopus2-s2.0-84957705255
dc.identifier.scopusqualityQ3
dc.identifier.startpage1277
dc.identifier.urihttps://doi.org/10.1055/s-0035-1560601
dc.identifier.urihttps://hdl.handle.net/20.500.14854/8229
dc.identifier.volume27
dc.identifier.wosWOS:000375004700028
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGeorg Thieme Verlag Kg
dc.relation.ispartofSynlett
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectcarbazole
dc.subjectpyrrolocarbazole
dc.subjectHemetsberger indolization
dc.subjectHT29 cells
dc.subjectcyctotoxicity
dc.titleSynthesis of Novel Pyrrolo[3,2-c]carbazole and Dipyrrolo[3,2-c: 2?,3?-g]carbazole Derivatives
dc.typeArticle

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