A NEW POTENTIOMETRIC SENSOR FOR THE ASSAY OF P53 IN BLOOD SAMPLES

dc.contributor.authorAl-Ogaidi, Ahmed Jassim Muklive
dc.contributor.authorStaden, Raluca-Ioana Stefan-Van
dc.contributor.authorGugoasa, Livia Alexandra
dc.contributor.authorVan Staden, Jacobus Frederick
dc.contributor.authorYanik, Hulya
dc.contributor.authorGoksel, Meltem
dc.contributor.authorDurmuş, Mahmut
dc.date.accessioned2025-10-29T11:37:31Z
dc.date.issued2017
dc.departmentFakülteler, Temel Bilimler Fakültesi, Kimya Bölümü
dc.description.abstractA potentiometric sensor based on graphite paste modified with a phthalocyanine-BODIPY conjugate was proposed for the assay of tumor suppressor P53. The working concentration range was between 1.17x10(-9) and 2.93x10(-8)x g/mu L with a slope of 82.62mV/mu g mL(-1) and a limit of detection was 3.37x10(-10)xg/mu L. The selectivity of the sensor was checked against possible interfering species from blood samples. The sensor was applied for the analysis of P53 in whole blood samples, without any pretreatment of the sample.
dc.description.sponsorshipPNII Program Partnership MULTIMODESCREEN [22/2014]
dc.description.sponsorshipThis work was supported by PNII Program Partnership 2014-2016, MULTIMODESCREEN, Contract no. 22/2014.
dc.identifier.endpage120
dc.identifier.issn1454-2331
dc.identifier.issue2
dc.identifier.orcid0000-0001-6570-3426
dc.identifier.orcid0000-0002-3264-2548
dc.identifier.scopus2-s2.0-85020303236
dc.identifier.scopusqualityQ4
dc.identifier.startpage113
dc.identifier.urihttps://hdl.handle.net/20.500.14854/13867
dc.identifier.volume79
dc.identifier.wosWOS:000405523600011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPolytechnic Univ Bucharest
dc.relation.ispartofUniversity Politehnica of Bucharest Scientific Bulletin Series B-Chemistry and Materials Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectP53
dc.subjectcolon cancer
dc.subjectpotentiometric sensor
dc.subjectblood samples
dc.titleA NEW POTENTIOMETRIC SENSOR FOR THE ASSAY OF P53 IN BLOOD SAMPLES
dc.typeArticle

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