Design of an amphiphilic porphyrin exhibiting high in vitro photocytotoxicity
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Tarih
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Royal Soc Chemistry
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A porphyrin monosubstituted by three triethyleneglycol chains grafted on a pentaerythritol skeleton was designed to display an optimized amphiphilicity for an enhanced cellular uptake and thus to exert enhanced photocytotoxicity. This porphyrin proved to be an excellent photosensitiser with submicromolar IC50.
Açıklama
Anahtar Kelimeler
Photodynamic Therapy, Phthalocyanine, Photosensitizers, Nanoparticles, Conjugate, Membrane, Yields
Kaynak
New Journal of Chemistry
WoS Q Değeri
Scopus Q Değeri
Cilt
40
Sayı
3
