Cyclotriphosphazene, a scaffold for 19F MRI contrast agents

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dc.contributor.authorOnal, Emel
dc.contributor.authorZhang, Cheng
dc.contributor.authorDavarci, Derya
dc.contributor.authorIsci, Umit
dc.contributor.authorPilet, Guillaume
dc.contributor.authorWhittaker, Andrew K.
dc.contributor.authorDumoulin, Fabienne
dc.date.accessioned2025-10-29T11:21:20Z
dc.date.issued2018
dc.departmentGebze Teknik Üniversitesi
dc.description.abstractA cyclotriphosphazene substituted with six 3,5-bis(trifluoromethyl) benzyloxy units was designed as a novel F-19 MRI contrast agent. The resulting molecule has 36 magnetically equivalent fluorine atoms and exhibited suitable MRI properties with high imaging sensitivity, confirming the proof-of-concept as a convenient scaffold for the production of new F-19 MRI contrasts agents. (C) 2017 Elsevier Ltd. All rights reserved.
dc.description.sponsorshipTurkish Academy of Sciences
dc.description.sponsorshipAustralian Research Council [CE140100036]
dc.description.sponsorshipAustralian Research Council [CE140100036] Funding Source: Australian Research Council
dc.description.sponsorshipF.D. thanks the Turkish Academy of Sciences for partial support. A.W. and C.Z. acknowledge the Australian Research Council (CE140100036) for funding of this research. We also acknowledge use of equipment managed by the Australian National Fabrication Facility, Queensland Node.
dc.identifier.doi10.1016/j.tetlet.2017.12.032
dc.identifier.endpage523
dc.identifier.issn0040-4039
dc.identifier.issn1873-3581
dc.identifier.issue6
dc.identifier.orcid0000-0002-2722-7497
dc.identifier.orcid0000-0002-6285-0524
dc.identifier.orcid0000-0002-0388-8338
dc.identifier.orcid0000-0002-0407-9604
dc.identifier.scopus2-s2.0-85039840131
dc.identifier.scopusqualityQ3
dc.identifier.startpage521
dc.identifier.urihttps://doi.org/10.1016/j.tetlet.2017.12.032
dc.identifier.urihttps://hdl.handle.net/20.500.14854/8990
dc.identifier.volume59
dc.identifier.wosWOS:000424853400006
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofTetrahedron Letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20251020
dc.subjectF-19 MRI
dc.subjectCyclotriphosphazene
dc.subjectContrast agent
dc.titleCyclotriphosphazene, a scaffold for 19F MRI contrast agents
dc.typeArticle

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